Associate Director, Downstream Process Development at Sutro Biopharma, Inc in San Francisco, CA
Sutro Biopharma, Inc. is looking for a technical leader who will report to the Senior Director of Downstream Process Development. You will be working to develop new downstream processes to maximize our technology and enhance our internal and collaborative product development initiatives in a fast-paced environment. Responsibilities Lead, mentor, coach and develop technical staff in all aspects of downstream process development, including protein purification, conjugation and new technology development. Design and execute to develop efficient and effective downstream recovery and purification processes. New technology development Support authoring and review of relevant CMC sections of regulatory submissions (IND, INDa, BLA) Transfer downstream processes to Sutro's manufacturing site, CMOs, and/or partner sites Represent Downstream Process Development on cross-functional teams Produce significant documents or publications (internal/external) supporting company policies and goals Present information and data in both written and verbal form Qualifications BS, MS or PhD in chemical engineering, life sciences or equivalent with at least 10
years (BS, MS) or 6-8
years (PhD) of biopharmaceutical industry experience in protein purification (including multiple modes of chromatography, depth and membrane filtration and ultrafiltration/TFF). Extensive knowledge of product variant and process-related impurity removal strategies expected. Extensive experience in scaling up, transferring, and supporting purification processes from bench scale to pilot and/or commercial scale. Understanding of GMP requirements. Experience with statistical design of experiments, advanced data analysis, process validation and Quality by Design concepts. Experience with protein conjugation process chemistry and protein formulation is preferred, but not required. Strong ability in execution and driving for results independently. Detail oriented with good organizational skills and able to work in a high paced team environment to meet deadlines and prioritize work on multiple projects. At least 3
years of experience supervising technical staff (direct and matrix management) with strong management and leadership skills. Excellent communication skills, both verbal and written, and the ability to build and maintain relationships with team members, partners, customers, and collaborators.
Salary Range:
$150K -- $200K
Minimum Qualification
Life SciencesEstimated Salary: $20 to $28 per hour based on qualifications.
years (BS, MS) or 6-8
years (PhD) of biopharmaceutical industry experience in protein purification (including multiple modes of chromatography, depth and membrane filtration and ultrafiltration/TFF). Extensive knowledge of product variant and process-related impurity removal strategies expected. Extensive experience in scaling up, transferring, and supporting purification processes from bench scale to pilot and/or commercial scale. Understanding of GMP requirements. Experience with statistical design of experiments, advanced data analysis, process validation and Quality by Design concepts. Experience with protein conjugation process chemistry and protein formulation is preferred, but not required. Strong ability in execution and driving for results independently. Detail oriented with good organizational skills and able to work in a high paced team environment to meet deadlines and prioritize work on multiple projects. At least 3
years of experience supervising technical staff (direct and matrix management) with strong management and leadership skills. Excellent communication skills, both verbal and written, and the ability to build and maintain relationships with team members, partners, customers, and collaborators.
Salary Range:
$150K -- $200K
Minimum Qualification
Life SciencesEstimated Salary: $20 to $28 per hour based on qualifications.
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